I am looking into developing an MCMC tool on GPUs using Python, so clearly pycuda is a great place to start. I am new to Python, but not to GPU programming. Following the online instructions I have attempted to install and test pycuda version 2013-1.1. The installation runs smoothly however when I run any of the tests (or examples) I receive the error: UnicodeDecodeError: 'utf8' codec can't decode byte ... (I have attached a log file of the errors from the running of test_cumath.py). I am using mac os x 10.6.8 (snow leopard), python 2.7.5 (2.6.1 has the same problem), CUDA 4.0. All of my C based GPU code runs smoothly as does all other python scripts I have. It is only pycuda that I am having issues with. Hopefully I have provided enough information, if you need more details please ask. Thank you for your time, I appreciate any help I can get